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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi
कॉल सेंटर:  011-26589142

एम्‍स के बारे में

Dr. Deepak Pandey

Name & Designation:    Dr. Deepak Pandey,   Scientist-II,

                                           Department of Reproductive Biology,

                     AIIMS, New Delhi.-29

 

Contacts:  Email: यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.  ,  यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

                 Phone: +91 11 2659 3941

 

Qualifications:

  • Ph.D. (Biotechnology), Himachal Pradesh University, Shimla, India (2011).
  • M.Sc. (Biotechnology), Himachal Pradesh University (HPU), Shimla, India (2005).

 

Professional training and past positions:

  • Worked as Scientist-B at Central Tasar Research & Training institute, Ranchi, Central Silk Board, Ministry of Textiles, Govt. of India (from November 5, 2015 to September 12, 2016).
  • Worked as Research Associate on the project entitled “Function of caseinolytic proteases in Mycobacterium tuberculosis pathogenesis” at National Institute of Immunology, New Delhi India (from August 5, 2011 to September 30, 2014).

 

Research interests:

  • Prostate pathologies (BPH & prostate cancer).
  • Ovarian cancer.

 

Research Summary:

The research focus of our lab is on benign prostatic hyperplasia (BPH) and prostate cancer with special emphasis on the interaction between prostate stromal and epithelial cells. As men age, there is a typical alteration in the ratio of estradiol to dihydrotestosterone (DHT). Under the altered levels of these hormones, stromal cells secrete certain paracrine factors that cause proliferation of epithelial cells and lead to either BPH or prostate cancer. This altered stromal-epithelial interaction occurring in vivo is being studied in vitro by culturing the normal prostate stromal and epithelial cell lines. In addition to this, we are interested in identification, characterisation and validation of novel proteins and mi-RNAs as non-invasive biomarkers for prostate pathologies.

 

Group Members (Past & Present):

Ankit Roychoudhury, Abhishek Singh Yadav, Muninagesh Alapakam, Afsa Junaid  

 

Projects: ongoing, submitted and past:

  • ICMR funded (42.3 Lakhs) project approved in March 2020. To elucidate the impact of micronutrients and vitamins on sex-steroid mediated stromal-epithelial interaction in prostate cells: role in maintenance of normal prostate physiology.
  • ICMR funded (91 Lakhs) 2019-2022. Clinico-genetic prognostic signatures for development of metastatic Castration Resistant Prostate Cancer (as Co-Investigator). 
  • AIIMS funded (10 Lakhs) 2017-2019. To study the effects of dietary flavonoids on prostate epithelial cells growing under the influence of prostate stromal cells.

 

Awards/Honours/Fellowships:

  • Awarded Scholarship from Department of Biotechnology (DBT), Govt. of India for pursuing MSc Biotechnology, 2003
  • Awarded Junior Research Fellowship (JRF), Indian Council of Medical Research (ICMR), 2006
  • Awarded Senior Research Fellowship (SRF), Indian Council of Medical Research (ICMR), 2008
  • Qualified ICMR-JRF (2005)
  • Qualified GATE (Graduate Aptitude Test in Engineering) in life sciences with 97.40 percentile and All India Rank-275 (2006).
  • Qualified DBT-JRF (2006)
  • Qualified National Eligibility Test (NET- June, 2015) in life science with All India Rank-18

 

Selected Publications:

  1. Pandey D*, Patel SKS, Singh R, Kumar P, Thakur V, Chand D* (2019). Solvent-tolerant acyltransferase from Bacillus sp. APB-6: Purification and Characterization. Indian J Microbiol; 59 (4): 500–507. (doi:  10.1007/s12088-019-00836-8: * Co-Corresponding author)
  2. Choudhury AR, Gupta S, Chaturvedi PK, Kumar N, Pandey D* (2019). Mechanobiology of cancer stem cells and their niche. Cancer Microenviron; (doi: 10.1007/s12307-019-00222-4: *Corresponding author)
  3. Choudhury AR, Kumar N, Sandeep K, Pandey D* (2019). Stem cell repertoire in the prostate epithelium. J Stem Cell Res Ther; 5(2): 44-46. (doi: 10.15406/jsrt.2019.05.00133: *Corresponding author)
  4. Singh PK, Yadav VK, Kalia M, Sharma D, Pandey D, Agarwal V (2019). Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone triggers mitochondrial dysfunction and apoptosis in neutrophils through calcium signaling. Med Microbiol Immunol; 208(6): 855-868. (doi: 10.1007/s00430-019-00631-8)
  5. Kumar P, Singh B, Thakur V, Thakur A, Thakur N, Pandey D, Chand D (2019). Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region. Biotechnol Rep; 15; 24: e00395. (doi: 10.1016/j.btre.2019.e00395)
  6. Yadav D, Sandeep K, Pandey D. Monoclonal Antibodies. In: Sharma AK, Kesarwani RK, Dutt R (Eds). Nanotechnology and Targeted Drug Delivery System. First edition. Studera Press: Delhi; 2019: pp 321-337.
  7. Singh R, Pandey D, Dhariwal S, Sood P, Chand D (2018). Bioconversion of acrylonitrile using nitrile hydratase activity of Bacillus sp. APB-6. 3 Biotech; 8(5): 225 (doi: 10.1007/s13205-018-1207-1)
  8. Singh R, Pandey D, Devi N, Chand D (2018). Bench scale production of butyramide using free and immobilized cells of Bacillus sp. APB-6. Bioprocess Biosyst Eng; (doi:10.1007/s00449-018-1951-y)
  9. Kumar N, Pandey D, Halder A (2018). Preventive, diagnostic and therapeutic applications of baculovirus expression vector system. In: Kumar D, Gong C (Eds). Trends in Insect Molecular Biology and Biotechnology. First edition. Austria: Springer: pp 163-191.
  10. Choudhury AR, Kumar N, Sandeep K, Pandey D* (2017). Biotechnological Potential of Stem Cells. J Stem Cell Res Ther; 3(1): 212-219. (doi: 10.15406/jsrt.2017.03.00090: *Corresponding author)
  11. Kumar P, Pandey D, Thakur V, Thakur A, Chand D (2017). Hyperproduction of tannin acylhydrolase in submerged fermentation from Aspergillus fumigatus. J Adv Microbiol; 3(2): 60-77 (ISSN Online: 2349-7785) 
  12. 12. Yadav D, Sandeep K, Pandey D, Dutta RK (2017). Liposomes for Drug Delivery. J Biotechnol Biomater; 7: 276. (doi: 10.4172/2155- 952X.1000276) 
  13. Pandey D, Singh R and Chand D (2011). An improved bioprocess for synthesis of acetohydroxamic acid using DTT (dithiothreitol) treated resting cells of Bacillus sp. APB-6. Bioresour Technol. 102, 6579–6586. (doi: 10.1016/j.biortech.2011.03.071)

DR. SURABHI GUPTA

Name:                                     DR. SURABHI GUPTA

Designation:                          Associate Professor

Institute/University:             Dept. of Reproductive Biology, AIIMS, New Delhi, INDIA

Email address:                       यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

 

Education (Post-Graduation onwards & Professional Career)

SN

Institution

Degree

Year

Field of Study

1

Banaras Hindu University, Varanasi, India

M.Sc.

1995

Biotechnology

2

All India Institute of Medical Sciences, New Delhi, India

Ph.D.

2002

Biochemistry

Thesis Title: -Expression of Cell Adhesion Molecules & Integrins in Trophoblast Cells

 

Position and Employment (Starting with the most recent employment)

SN

Institution

Position

From (Date)

To (date)

1

Dept of Reproductive Biology, AIIMS, New Delhi, India.

Associate Professor

July, 2017

Till date

2

Dept of Reproductive Biology, AIIMS, New Delhi, India.

Assistant Professor

2014

2017

3

Dept of Gastroenterology, AIIMS, New Delhi, India.

Senior Research Officer

2013

2014

4

Dept of Gastroenterology, AIIMS, New Delhi, India.

Research Associate

2011

2013

5

Molecular & Cellular Biology, College of Biological Sciences, University of California Davis, Davis, CA, USA.

Post-Doctoral Researcher

2002

2009

6

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Post-Doctoral Research Fellow

2001

2002


Publications

Journal Articles:

  1. Bodhana Dhole, Surabhi Gupta, Skand Shekhar, Anand Kumar. A novel antigonadotropic role of Thyroid Stimulating Hormone on Leydig cell – derived Mouse Leydig Tumor Cells – 1 line. Annals of National Academy of Medical Sciences (India). 2020; 56: 30-37.

  2. Nidhi Singh, Sumaira Rashid, Safoora Rashid, Nihar Ranjan Dash, Surabhi Gupta, Anoop Saraya. Clinical significance of promoter methylation status of tumor suppressor genes in circulating DNA of pancreatic cancer patients. Journal of Cancer Research and Clinical Oncology. 2020; 146(4): 897-907. doi: 10.1007/s00432-020-03169-y.

  3. Ankit Roy Choudhury, Surabhi Gupta, Pradeep Kumar Chaturvedi, Neeraj Kumar, Deepak Pandey. Mechanobiology of cancer stem cells and their niche. Cancer Microenvironment. 2019; 12(1): 17-27. doi: 10.1007/s12307-019-00222-4.

  4. Bodhana Dhole, Surabhi Gupta, Senthil Kumar Venugopal, Anand Kumar. Triiodothyronine stimulates VEGF expression and secretion via steroids and HIF-1α in murine Leydig cells. Systems Biology in Reproductive Medicine. 2018; 64(3): 191-201. doi: 10.1080/19396368.2018.1433248.

  5. Sumaira Rashid*, Nidhi Singh*, Surabhi Gupta*, Safoora Rashid, Nandini Nalika, Vikas Sachdev, Chandra Sekhar Bal, Siddhartha Datta Gupta, Shyam S. Chauhan, Anoop Saraya. Progression of Chronic Pancreatitis to Pancreatic Cancer: Is There a Role of Gene Mutations as a Screening Tool? Pancreas. 2018; 47(2): 227-232. [*Co-first authors]

  6. Nidhi Singh, Surabhi Gupta, Ravindra M. Pandey, Peush Sahni, Shyam S. Chauhan, Anoop Saraya. Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients. Indian Journal of Medical Research. 2017 Sep; 146: 334-340.

  7. Nidhi Singh, Surabhi Gupta, R M Pandey, Shyam S Chauhan and Anoop Saraya. High levels of cell-free circulating nucleic acids in pancreatic cancer are associated with vascular encasement, metastasis and poor survival. Cancer Investigation. 2015 Mar; 33(3): 78-85.

  8.  Nidhi Singh, Prasenjit Das, Surabhi Gupta, Vikas Sachdev, Siddhartha Srivasatava, Siddhartha Datta Gupta, R. M. Pandey, Shyam S. Chauhan, Anoop Saraya. Plasma Cathepsin L: A Prognostic Marker for Pancreatic Ductal Adenocarcinoma. World J Gastroenterol. 2014; 20(46): 17532-40.

  9. Nidhi Singh, Prasenjit Das, Surabhi Gupta, Siddhartha Datta Gupta, Peush Sahni, R M Pandey, Shyam S Chauhan and Anoop Saraya. Prognostic significance of extracellular matrix degrading enzymes – Cathepsin L and matrix metalloproteases-2 [MMP-2] in human pancreatic cancer. Cancer Investigation. 2013; 31(7): 461-71.

  10. Hitoshi Nishimura, Surabhi Gupta, Diana G Myles and Paul Primakoff. Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins. Reproduction. 2011; 141(4): 437-51.

  11.  Diego A Ellerman, Jimin Pei, Surabhi Gupta, William J Snell, Diana G Myles, Paul Primakoff. Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm. Mol Reprod Dev. 2009; 76(12): 1188-99.

  12. Guo Z Zhu, Surabhi Gupta, DG Myles, P Primakoff. Testase 1 (ADAM 24) a sperm surface metalloprotease is required for normal fertility in mice. Mol Reprod Dev. 2009; 76: 1106-14.

  13. Surabhi Gupta, Paul Primakoff, Diana G Myles. Can the presence of wild-type oocytes during insemination rescue the fusion defect of CD9 null oocytes? Mol Reprod Dev. 2009; 76(7): 602.

  14. Zhiyong He, Surabhi Gupta, Diana G. Myles, Paul Primakoff. Loss of EWI-2 on the surface of CD9 null oocytes. Mol Reprod Dev. 2009; 76(7): 629-36.

  15. Kathryn E. Runge, JE. Evans, Zhiyong He, Surabhi Gupta, KL McDonald, Henning Stahlberg, P Primakoff, Diana G. Myles. Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution. Developmental Biology. 2007; 304: 317-25.

  16. Michael J. Misamore, Surabhi Gupta, William J. Snell. The Chlamydomonas Fus1 protein is present on the mating type plus fusion organelle and required for a critical membrane adhesion event during fusion with minus gametes. Molecular Biology of Cell. 2003; 14(6): 2530-42.

  17. Chandana Das, V. Senthil Kumar, Surabhi Gupta, Sunesh Kumar. Network of cytokines, integrins and hormones in human trophoblast cells. Journal of Reproductive Immunology. 2002; 53(1-2): 257-68.

  18. Chandana Das, V Senthil Kumar, S Basak, Surabhi Gupta, Sunesh Kumar. Immunobiology of trophoblast cells. Indian Journal of Clinical Biochemistry. 2000; 15(suppl.): 60-64.

  19. Surabhi Gupta, V. Senthil Kumar and Chandana Das. Expression and modulation of cell adhesion molecules in trophoblast cells. The Immunologist. 1998; Suppl. 1: 68.

  20. V. Senthil Kumar, Surabhi Gupta and Chandana Das. Interleukins in maternal-fetal interaction. The Immunologist. 1998; Suppl. 1: 69.

  21. V Senthil Kumar, Surabhi Gupta and C Das. Endotoxin regulated expression of interleukins in human trophoblast cells. American Journal of Reproductive Immunology. 1998; 40: 263.

Book Chapters:

1. Surabhi Gupta, Mona Sharma, Anand Kumar. Seminal Vesicles. In: Basics of Human Andrology: A Textbook. Eds: Anand Kumar & Mona Sharma. Publisher: Springer (2017) ISBN: 978-981-10-3694-1.

2. Surabhi Gupta, Anand Kumar. Genital Ducts and Other Accessory Sex Glands. In: Basics of Human Andrology: A Textbook. Eds: Anand Kumar & Mona Sharma. Publisher: Springer (2017) ISBN: 978-981-10-3694-1.

3. Surabhi Gupta, Anand Kumar. The Human Semen. In: Basics of Human Andrology: A Textbook. Eds: Anand Kumar & Mona Sharma. Publisher: Springer (2017) ISBN: 978-981-10-3694-1.

4. Surabhi Gupta, Anand Kumar. Systemic Influences on Male Reproduction - Immune System. In: Basics of Human Andrology: A Textbook. Eds: Anand Kumar & Mona Sharma. Publisher: Springer (2017) ISBN: 978-981-10-3694-1.

5. Mona Sharma, Surabhi Gupta, Bodhana Dhole, Anand Kumar. The Prostate Gland. In: Basics of Human Andrology: A Textbook. Eds: Anand Kumar & Mona Sharma. Publisher: Springer (2017) ISBN: 978-981-10-3694-1. 

Ongoing Research Grants

Surabhi Gupta (PI). Embryo-uterine cross-talk for implantation & beyond: Role for exosomal microRNAs. DST-SERB 2018-2021.

Surabhi Gupta (PI). Generation of genome-edited mice using CRISPR/Cas-9 based knock-out/knock-in technology to study mammalian sperm-egg fusion. DBT 2017–2020. 

Completed Research Grants

Surabhi Gupta (PI). Role of 3,5,3’-L-triiodothyronine (T3) in the modulation of VEGF expression and leydig cell function. DBT 2016 – 2019

 

 

 

Dr. Mona Sharma

 

    Dr. Mona Sharma   MD, DNB, MAMS      

                                            Associate Professor                                                

Department of Reproductive Biology,

Room no. 2087, 2nd Floor, Teaching Block

                                 AIIMS, New Delhi                                      

Email: यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

9968147821

 

PROFESSIONAL QUALIFICATION                                                    

  1. DNB (Anatomy) from National Board of Examinations in 2013.
  2. MD (Anatomy) from All India Institute of Medical Sciences (AIIMS), New Delhi in May, 2009
  3. MBBS from Kasturba Medical College, MAHE, Mangalore, Karnataka in 2003.

 

EMPLOYMENT DETAILS  

  1. Associate Professor in the Department of Reproductive Biology from July 1, 2017 till date.
  2. Assistant Professor in the Department of Reproductive Biology from May 23, 2014 to June 30 2017. 
  3. Assistant Professor at Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi from September 25, 2012 to May 22, 2014.
  4. Senior Residency at AIIMS, New Delhi from June 12, 2009 to June 11, 2012.

 

RESEARCH WORK  

  1. Principal investigator: High Resolution Sex Chromosome Genome Analysis in Pathogenesis of Premature Ovarian Failure (A-360).
  2. Principal investigator: Study of potential sperm factors and related signaling pathways in eliciting oocyte intracellular calcium rise (A-631).
  3. Chief-guide: Mutational Analysis of HS6ST2: A Candidate Gene in Idiopathic Premature Ovarian Failure.
  4. Chief-guide: Effect of L-acetyl carnitine on TNF-α Induced Apoptosis in mice follicles.
  5. Chief-guide: Citrate synthase expression in human sperm and oocyte activation in mice.
  6. Chief-guide: Role of L-carnitine in oocyte activation.
  7. Chief-guide: Effect of sperm vitrification on PLC-zeta expression.
  8. Co-guide: Epigenetic changes during epithelial to mesenchymal transition in trophoblast cells under physiological and pathological conditions.
  9. Co-guide: A correlative study of feto-maternal hydrogen sulfide production with umbilical artery velocimetry in preeclampsia.
  10. Co-guide:  Pre and post-vasectomy sperm parameters.
  11. Co-guide: Effect of tyrosine kinase inhibitors on sperm parameters and pituitary gonadal axis in males with chronic myelois leukemia.
  12. Co-guide: Etiopathology of hyperprolactinemia.
  13. Co-guide: Biomarkers in polycystic ovarian syndrome.
  14. Co-guide: Genomics and epigenomics of polycystic ovarian syndrome
  15. Co-guide: Role of placental derived exosomes in decidualization in recurrent pregnancy loss patients
  16. Co-guide: Genetic determinants of premature ovarian failure patients.
  17. Thesis research: “Apoptosis in Trophoblastic Cells of Human Placenta in Preeclampsia”
  18. DC member: Role of micro RNA-30 in cystathionine gamma lyase mediated trophoblast cell invasion and status in preeclampsia.
  19. DC member: To elucidate the role of osteoimmune system in regulating fertility
  20. DC member: Delineating the role of insulin/insulin like growth factor signaling in C.elegans reproductive aging.
  21. DC member: HDAC inhibitors mediated genome-wide dynamics in c.elegans embryogenesis and aging.
  22. DC member: Characterization of TEX29 protein and its potential role in mammalian fertilization.
  23. Embryological basis of anatomical variations in humans as part of UG, PG teaching program. 

 

PROJECTS

AIIMS intramural research funding:

Completed: Intramural project titled “High Resolution Sex Chromosome Genome Analysis in pathogenesis of Premature Ovarian Failure” (array cGH)

Ongoing: Intramural project titled “Study of potential sperm factors and related signaling pathways in eliciting oocyte intracellular calcium rise.” (Heterologous ICSI) 

Technically approved” Role of mitochondrial fatty acid shuttle system in premature ovarian failure”DHR/GIA

 

PUBLICATIONS  

  1. Asuri K, Mohammad A, Prajapati OP, Sagar R, Kumar A, Sharma M, Chaturvedi PK, Gupta SV, Rai SK, Misra MC, Bansal VK. A prospective randomized comparison of sexual function and semen analysis following laparoscopic totally extraperitoneal (TEP) and transabdominal pre‑peritoneal (TAPP) inguinal hernia repair. Surg.endo.2020. https://doi.org/10.1007/s00464-020-07733-y
  2. Rishi I, Halder A, Sharma JB, Jain M and Sharma M. Single Strand Conformation Polymorphism and sequencing to detect HS6ST2 gene mutations in patients of idiopathic premature ovarian failure.JCDR; Jan 2020:1-9.
  3. Sharma Y, Sharma M. Sperm Cryopreservation: Principles and Biology. Accepted for publication in Journal of infertility and Reproductive biology, 2020.
  4. Sharma M. Assisted oocyte activation. March 2019; Indian Fertility Society.
  5. Sharma M. Recent evidence for PGS/PGD; July 2019; Indian Fertility Society.
  6. Sharma M. Oocyte Activation following Intracytoplasmic Sperm Injection: Current Status from Bench to Bedside; 2019; Indian Society for the study of Reproduction and Fertility.
  7. Kumar A, Sharma M. Basics of Human Andrology. 1st ed. Springer Nature, Singapore. 2017; 1-536.
  8. Sharma M, Gupta S, Dhole B, Kumar A. The Prostate gland. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 17-35
  9. Gupta S, Sharma M, Kumar A. Seminal Vesicles. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 37-45.
  10. Sharma M, Kumar A. Neurovascular supply and lymphatic drainage of male reproductive organs. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 55-65.
  11. Sharma M, Kumar A. The Sperm. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 171-203.
  12. Sharma M, Kumar A. Male Sexual Function. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 251-281.
  13. Sharma M, Chadda RK, Anish PK,  Kumar A. Male Behaviors I: Brain areas regulating male behaviors. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 293-313.
  14. Sharma M, Kumar A. Male II: Neural pathways regulating male behaviors Behaviors. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 315-339.
  15. Sharma M, Kumar A. Male Behaviors III: Brain polymorphism and sexual orientation. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 341-347.
  16. Sharma M, Kumar A. Male Behaviors IV: Ageing brain. In: Basics of Human Andrology, 1st ed. Kumar and Sharma, eds. Springer Nature, Singapore. 2017; 349-362.
  17. Shivi Goel, Jyoti Arora, Vandana Mehta, Mona Sharma, Rajesh Kumar Suri and Gayatri Rath. Unusual disposition of lateral circumflex femoral artery – anatomical description and clinical implications. World J Clin Cases 2015 January 16; 3(1): 85-88.
  18. R. Hansdak, J. Arora, M. Sharma, V. Mehta, R K Suri, S. Das. Unusual branching pattern of brachial artery-Embryological basis and clinicoanatomical insight. La Clinica Terapeutica,March 2015, 166: 2;65-7.
  19. Shivi Goel, Jyoti Arora, Vandana Mehta, Mona Sharma, Rajesh Kumar Suri and Gayatri Rath, Das S. Adductor accessorius- an unusual supernumerary adductor muscles of thigh. La Clinica Terapeutica, 2015, May-Jun;166 (3): 117-7.
  20. Rustagi SM, Sharma M, Singh N, Mehta V, Suri R, Rath G. Peripheral communications   of the Intercostobrachial Nerve in relation to the Alar Thoracic Artery. Advanced Medical Research, Feb 2015, 1-4.
  21. Gandhi S, Sharma M, Pakhiddey R, Thakur A, Mehta V, Suri R, Rath G. Unduly extensive uncinate process of pancreas in conjunction with pancreatico- duodenal fold. Anat Cell Biol, March 2015; 48: 81-83. 
  22. Sharma M, Hansdak R, Mehta V, Arora J, Suri R, Rath G. An unusual branching pattern of the median cubital vein and its relations with lateral cutaneous nerve of forearm in the upper extremity-anatomicoclinical notes. JSA, 2014 (4)1:49-53. 
  23. Mona S, Renu D. Possible developmental origin and clinical implications of a brachial plexus variation. GJRA; 3(2): 60-62, 2014. 
  24. Thakur A, Tapas S, Sharma M, Mehta V, Suri R, Rath G. Anatomical description of a variant abductor digiti minimi accessorious muscle and its clinical correlation with ulnar neurovascular entrapment syndrome. Journal of Surgical Academia 2014; 4(2):41-44. 
  25. Sharma M, Kumar R, Dhingra R. “Apoptosis: Researching the clinical implications”. JIMSA July-Sept. 2014;27(3). 
  26. Gandhi S, Sharma M, Pakhiddey R, Mehta V, Suri RK, Rath G. “Unilateral aberrant gonadal venous anatomy coexistent with a distinct intrarenal cleft”. OA Anatomy 2013 Nov 01;1(3):28.
  27. Sharma M, Kumar R, Bhatla N, Dhingra R. "A Comparative study of apoptosis in placentas of normal and preeclamptic Indian pregnant women by TUNEL assay and M30 immunostaining.  Journal of clinical laboratory analysis; 2012: 26: 459-466.
  28. Sharma M, Kumar R, Dhingra R. “An immunohistochemical study of the syncytial knots in the preeclamptic placentas". International journal of pharmaceutical research and bioscience; 2012: 1(4) 228-239.
  29. Sharma M, Dhingra R, Kumar R. “Relevance of placental pathological changes of maternal inflammatory syndrome along with the obstetric and clinical parameters in preeclampsia”. International journal of scientific and research publications, 2012; 2(8): 313-320.
  30. Sharma M, Kumar R, Dhingra R. “Apoptosis: Understanding of the signaling pathways”. International journal of biological and medical research. 2012; 3(3):2029--2031.
  31. Sharma M, Kumar R, Dhingra R. “Apoptosis: Searching for the detection techniques”. International journal of biological and medical research. 2012; 3(3):2172-2175.

 

AWARDS AND ACHIEVEMENTS

Best Poster Award for paper titled “Role of l-carnitine in TNF-α induced mice oocyte apoptosis” Rana R, Halder A, Sharma M; at ISSRF World congress,  February 2020 at ICMR-SMVDU, Centre for Advanced Research, SMVDU, Katra. Jammu & Kashmir, India

Best Poster Award for paper titled“Evaluation of Parameters to Standardize Single Strand Conformation Polymorphism for Detecting Gene Mutations in Patients of Idiopathic Premature Ovarian Failure”.  Isha Rishi, J B Sharma, Manish Jain, Mona Sharma,  at ISSRF, 2019, JNU, New Delhi

Elected as member of National Academy of Medical Sciences

Reviewer of a book proposal titled “Molecular mechanisms in spermatogenesis and male infertility” submitted to CRC Press. 

Reviewer of a book proposal titled “Thyroid and human reproductive functions” submitted to CRC Press.

DBT project reviewer

Editor, Indian Fertility Society, Newsletter “ReproGenQ”

Memberships :

Academy of Clinical Embryologists

Indian Fertility Society

Endocrine Society of India

Indian Society for the Study of Reproduction and Fertility

Society for Reproductive Biology and Comparative Endocrinology 

Invited Talks

  1. Guest Lecture: “Puberty awareness”. In CME on child abuse, held on 12-11-19 in AIIMS, New Delhi
  2. Guest lecture on “Recent advances in infertility” on November 11, 2018 during 66th NATCON-ASI at AIIMS Rishikesh
  3. Guest Lecture on “Non invasive methods of preimplantation and prenatal diagnosis” on 4th April 2015 in the Department of Anatomy, VMMC & Safdarjung hospital, New Delhi.

 

PRADEEP KUMAR CHATURVEDI

PRADEEP KUMAR CHATURVEDI, MSc, PhD, MNAMS

Professor

Officer in Charge, CRIA Facility

Department of Reproductive Biology

All India Institute of Medical Sciences

New Delhi - 110 029

Phone: 2659 4363 Fax :26588663 mobile 9873395001

E-mail: यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.

 

Rockefeller foundation fellow 1991-1993

 PROFESSIONAL APPOINTMENTS:

July 2015 – Till date      Professor, Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi - 110029, India

 

Teaching Experiences:

·  More than 25 years of teaching

  • PhD Students: Three Chief Guide and Six as co Guide.
  • Md Thesis co supervisor: Nine
  • Teaching of MD laboratory Medicine, MD Biochemistry
  • Training of various laboratory techniques to post graduate students and scientist from various universities and institution
  • Setup centralized Instrumentation Lab in the department

 

Patient Care:

  • Providing service for in-house and outpatient for 46 parameters (Thyroid function, Reproductive hormones and cancer marker etc). Total no of test being done more than two lakhs per year
  • State of art Technology, Abbott system was brought in to provide quick and International quality results for in-house and out-patient for various hormones and markers
  • Setup Andrology lab in the department for providing services for patient care and research

 

HONOR/AWARDS: Best poster award to our poster at APPICON 2004 at Banglore.

  1. Rockefeller foundation Fellowship award USA, 1991-1993
  2. Senior Research Associate from Council of Scientific and Industrial Research, New Delhi, India.
  3. Member ship of National Academy of Medical Sciences 2012
  4. Best poster award at Andrology Conference at IIT Delhi 2011 
  5. Best poster award to our poster at APPICON 2004 at Bangalore 
  6. 3rd Best Poster Award in AIIMS Research Day 2019

Research Projects undertaken  

Research Projects

Source of funding

year

Rockefeller foundation USA

1994-1997

AIIMS Project

2006

ICMR Project SRF

2006

ICMR Project SRf

2010

DST Project co supervisor

2009

DST women fellow to Postdoc working with me

2011

HLL Life care Ltd/Pregnancy test kits Qc

2009 on wards

Mini of Health Pregnancy test kits Qc

2015 onwards

ICMR Effects of Non-ionizing Electro Magnetic Field (EMF) on Human Health (referral center

Up-to 2022

ICMR Phase II clinical trial with an intra-vasal injectable male contraceptive-RISUG

Up to 2020

 Research Projects as Co PIs  

Analysis of anti-cancer activity of herbal extracts on prostate cancer cell lines”.

Effect of Zinc and Vitamin D on prostrate epithelial cells growing under the influence of prostrate stromal cells

Role of miR-143-3p in modulating Trophoblast cell invasion

Reference range of serum alpha feto protein in Indian children below 3 years of age

Age specific nomogram of Anti mullerian Hormone and Antral follicle counts in infertile and fertile Indian women

 

List of Publications:  

Published

Abstract index

Non-Index

Editor/Associate of Books

Abstract Book

45

15

5

2

2

  MEMBERSHIP IN SCIENTIFIC SOCIETIES  

  1. Life Membership of National Academy of Medical Sciences
  2. Life Member of Indian Society for the Study of Reproduction and fertility
  3. Life Member of Andrology Society of India
  4. Life Member of Biotechnology Society of India
  5. Life member of APICON

 Conferences  

Organized 3 International conferences and attended number of conferences and presented papers  

Other Involvement:  

Member of Board of Studies of Biotechnology for session 2011-2012 of Mahamaya Technical University, Noida. Reviewer of projects of Department of Biotechnology (DBT). Member Selection Committee for projects ICMR. Reviewer of ICMR projects. PhD examiner IMTech Chandigarh, Guwahati University, Calcutta University, NDRI Karnal  

PERSONAL DATA  

Date of Birth               :           August 18th, 1958  

Publications   

  1. Krishna Asuri, Aamir Mohammad, Om Prakash Prajapati, Rajesh Sagar, Atin Kumar, Mona Sharma, Pradeep Kumar Chaturvedi, Shardool Vikram Gupta, Sanjeet Kumar Rai, Mahesh Chandra Misra,Virinder Kumar Bansal A prospective randomized comparison of sexual function and semen analysis following laparoscopic totally extraperitoneal (TEP) and transabdominal pre-peritoneal (TAPP) inguinal hernia repair Surgical Endoscopy doi.org/10.1007/s00464-020-07733-y
  2. Gupta V, Singh A, Khadgawat R, Agarwal A, Iqbal A, Mehtab W, Chaturvedi PK, Ahuja V, Makharia GK. The spectrum of clinical and subclinical endocrinopathies in treatment-naïve patients with celiac disease. Indian J Gastroenterol. 2019 Dec;38(6):518-526. doi: 10.1007/s12664-019-01006-w. Epub 2019 Dec 26.
  3. Soni S, Agarwal A, Singh A, Gupta V, Khadgawat R, Chaturvedi PK, Ahuja V, Makharia GK. Prevalence of thyroid autoimmunity in first-degree relatives of patients with celiac disease. Indian J Gastroenterol. 2019 Oct;38(5):450-455. doi: 10.1007/s12664-019-00990-3. Epub 2019 Nov 8.
  4. Roy Choudhury A, Gupta S, Chaturvedi PK, Kumar N, Pandey D.Mechanobiology of Cancer Stem Cells and Their Niche.Cancer Microenviron. 2019 Apr;12(1):17-27. doi: 10.1007/s12307-019-00222-4. Epub 2019 Apr 19. Review.
  5. Kalsi AK, Halder A, Jain M, Chaturvedi PK, Sharma JB. Prevalence and reproductive manifestations of macroprolactinemia Endocrine. 2019 Feb;63(2):332-340
  6. Kalsi AK, Halder A, Jain M, Chaturvedi PK, Mathew M, Sharma JB Association of raised levels of IL-4 and anti-TPO with hyperprolactinemia. Am J Reprod Immunol. 2019 Mar;81(3): e13085
  7. Ahuja K, Garg B, Chowdhuri B, Yadav RK, Chaturvedi PK. A Comparative Analysis of the Metabolic and Coagulative Profiles in Patients with Idiopathic Scoliosis, Congenital Scoliosis and Healthy Controls: A Case-Control Study Asian Spine J. 2018 Dec;12(6):1028-1036
  8. Suresh R, Wig N, Panda PK, Jyotsna VP, Chaturvedi PK, Pandey RM Serum Cortisol Level in Indian Patients with Severe Sepsis/Septic Shock. J Emerg Trauma Shock. 2017;10(4):194-198
  9. Niraj Pant, G Kumar, A. D. Upadhyay, Y. K. Gupta, P. K. Chaturvedi: Correlation between lead and cadmium concentration and semen quality. Andrologia, 2015 47(8): 887-91
  10. Niraj Pant, M Shukla, A. D. Upadhyay, P. K. Chaturvedi, D. K. Saxena, YK Gupta: Association between environmental exposure to p, p′-DDE and lindane and semen quality Environ Sci Pollut Res DOI 10.1007/s11356-014-2965-x, 2014 online, 2014,21(18)11009-16.
  11. Niraj Pant, G. Kumar, A. D. Upadhyay, D. K. Patel, Y. K. Gupta, P. K. Chaturvedi: Reproductive toxicity of lead, cadmium, and phthalate exposure in men Environ Sci Pollut Res DOI 10.1007/s11356-014-2986-5 ,2014 online. 2014, 21(18): 11066-74.
  12. Niraj Pant, AB Pant, P K Chaturvedi, M Shukla N Mathur YK Gupta and DK Saxena. Semen quality of environmentally exposed human population: The toxicological consequence Environ Sci Pollut res may21,2013 (online), 2013, 20(11): 8274-81.
  13. Bajpai M, Chaturvedi PK, Bal CS, Sharma MC, Kalaivani M. Posterior urethral valves: Persistent renin angiotensin system activation after valve ablation and role of pre-emptive therapy with angiotensin converting enzyme-inhibitors on renal recovery. J Indian Assoc Pediatr Surg. 2013 Apr;18(2):74-8. doi: 10.4103/0971-9261.109357.
  14. A Kumar, L Rani, B Dhole, P K Chaturvedi Oxygen as a regulator of MA-10 cell functions: effect of cobalt chloride on VEGF production. Andrologia 2012, 44; 615-620.
  15. Anand Kumar, Rupali Dewan, Jyotsna Suri, Suman Kohli, Skand Shekhar, Bodhana Dhole, Pradeep Kumar Chaturvedi Abolition of endocrine dimorphism in hyperthyroid males? An argument for the positive feedback effect of hyper estrogenemia on LH secretion. Andrologia 2012, 44; 217-225.
  16. Minu Bajpai, CS Bal, Rakesh Kumar, PK Chaturvedi, M Kalaivani Arun K Gupta Persistant rennin angiotensin system activation after anti reflux surgery and its management J Pediatric Urology 2011, Dec7(6): 616-22
  17. Lata Rani, BP Mohanty, P K Chaturvedi, Anand Kumar Hypoxic Modulation of LH action on MA-10 Cells in Book Molecular and clinical aspects of gonadal and nongonadal actions of gonadotropins” Eds CV Rao, USA, Anand Kumar, PK Chaturvedi 2010 Narosa Publishing House, New Delhi
  18. Gupta R, Deepanjali S, Kumar A, Dadhwal V, Agarwal SK, Pandey RM, Chaturvedi PK. A comparative study of pregnancy outcome and menstrual irregulaties in northern Indian patients with systemic lupus erthematosus and rheumatoid arthritis Rheumatol Int. 2010 Nov; 30(12): 1581-5. Epub 2009 Oct 14
  19. Garima Nirwal, Anand Kumar, Pradeep Kumar Chaturvedi Effect of hCG and cAMP on progesterone production in Leydig cells during hypoxic condition. Biology of Reproduction 2007 spl issue abstract 417
  20. Pradeep Kumar Chaturvedi Garima Nirwal, Anand Kumar, Effect of hypoxia on the VEGF secretion in MA-10 Leydig cells. Biology of Reproduction 2007 spl issue abstract 249
  21. Sharma SK, Kumpawat S, Goel A, Banga A, Ramakrishnan L, Chaturvedi P. Obesity, and not obstructive sleep apnea, is responsible for metabolic abnormalities in a cohort with sleep-disordered breathing. Sleep Med. 2007 Jan;8(1):12-7.
  22. Kumar A, Chaturvedi PK, Mohanty BP Hypoandrogenaemia is associated with subclinical hypothyroidism. Int. J Andrology 2007, 30(1), 14-20,
  23. Mohanty BP, Lata Rani, Chaturvedi PK, Kumar A Effect of cobalt chloride on steroidogenesis of MA-10 cells. Indan J Physiol Pharmacol 2006; 52 (5) 117.
  24. Jha A, Sharma SK, Tandon N, Lakshmy R, Kandhiravan T, Handa KK, Gupta R, Pandey RM and Chaturvedi P.K. Thyhyroxine replacement therapy reverse sleep-disordered breathing in patients with primary hypothyroidism. Sleep Medicine 2006 7(1): 55-61, Epub 2005 Sep 28.
  25. Kumar A, Halder A, Chaturvedi PK, Chiplunker A, Arora E, Shruti, Mohanty BP, Lata, Garima (2005). Results of Preclinical and Clinical trials of Asokarishta. Indian Journal of Physiology and Pharmacology, 9(5): 92. (Abstract)
  26. Kumar A Mohanty BP Chaturvedi PK: Regulation of hypophyseal gonadal axis in thyroid disorders. Indan J Physiol Pharmacol 2004; 48 (5) 223.
  27. Sharma RS, Rajalakshmi M, Pal PC, Roy S, Behal VK, Sharma DN, Chaturvedi PK, Pruthi JS.Evaluation of efficacy, safety, and reversibility of combination regimen of cyproterone acetate and testosterone buciclate in bonnet monkey. Contraception. 62:195-201, 2000.
  28. A. Kumar, N. Ahmad, P. Chaturvedi, S. Mittal and A. Farooq: Cyclic behaviour of splenic mononuclear cells (MNCs) in the regulation of granulosa cell progesterone (P4) production. Mol. Cell. Endo. (Suppl.) 164: 2000
  29. N. Ahmad, P. Chaturvedi and A. Kumar: Inhibition of bovine granulosa cell steroidogenesis by Mycobacterium tuberculosis (M.tb) in vitro. Mol. Cell. Endo. 164: 2000.
  30. A. Kumar, N. Ahmad and P. Chaturvedi: Modulation of granulosa cell steroidogenesis by microbes: an in vitro study. Mol. Cell. Endo. 164: 2000.
  31. P K Chaturvedi L Johnson: Architectural arrangement of stages within human seminiferous tubule is related to efficiency of spermatogenesis. Cell Tissue Res. 273, 65-70, 1993.
  32. P K Chaturvedi, Larry Johnson: Effect of age and daily sperm production on the architectural arrangements of stages of the spermatogenic cycle in human seminiferous tubule. J Andrology (Suppl) 1993.
  33. P K Chaturvedi, Wayne C Zeh, Charles A Proshek, Larry Johnson: Effect of age and testicular transplantation on Sertoli cell number in Fischer rats. Biol Rep (Suppl) 48 p94. 1993
  34. P K Chaturvedi and Larry Johnson: Relationship between the architectural makeup of seminiferous tubules and efficiency of spermatogenesis in men. J Andrology 1992; (Suppl)
  35. L Johnson, P K Chaturvedi and J D Williams: Missing generations of spermatocytes and spermatids in seminiferous epithelium contribute to low efficiency of spermatogenesis in humans. Biol Rep. 47, 1091-1098,1992.
  36. P K Chaturvedi, Vibhuti Purwar, T P Singh, R K Tandon: Orange peel oil is a potent cholesterol gallstone Solvent. Indian J Gastroenterology 1990;9:(suppl) A7.
  37. P K Chaturvedi, R V S Raju, T Rajindra Kumar, Vibhuti Purwar, T P Singh and Rakesh Tandon. A possible cause of pancreatic stone formation. Ind J Gastroenterology. 8 No 4 (SUPPL) A 12-13 (1989)
  38. Vibhuti Purwar, P K Chaturvedi, R V S Raju, P Augustine, and Rakesh Tandon. Biophysical, Biochemical and Morphological comparative study on bile duct stones of North and South Indian Origin. Ind J Gastroenterology. 8 No 4 (SUPPL) A 8-9. (1989).
  39. R V S Raju, P K Chaturvedi, Vibhuthi Purwar and Rakesh Tandon. Gall stone - sex dependent. Ind J Gastroenterology. 8 No 4 (SUPPL) A 37. (1989).
  40. S.S. Hassan P.K. Chaturvedi: Whole body X-irradiation and impact of dietary factors on brain and testes of albino rats. Strahlentherapaie 164, 37-43, 1988.
  41. S.S.Hassan, P.K. Chaturvedi, and A.K.S. Kushwaha: Radiprotective effect of neo-mercazole in the rats during starvation stress. Radiobiolia Radiotherapia 28, 367-379, 1987.
  42. P.K.Chaturvedi and S.S.Hassan : effect of two graded doses of X-irradiation on the rat adrenal gland and its protection by S-phenetyl formamidino 4( N-methyl isothioamide) morpholine dihydrochloride. Proc. Ind. Acad. Sci. 94, 523-526, 1985.
  43. S.S.Hassan and P.K.Chaturvedi : Irradiation effect on the adrenal gland of rat undergoing inanition stress. Proc. Ind. Acad. Sci. 94, 79-86, 1985.
  44. P.K.Chaturvedi and S.S.Hassan : 60 Co radiation induced hazards and use of S-anisyl formamidino 4(N-methyl isothioamide) morpholine dihydrochloride as chemical radioprotector. J. Nucl. Med. Allied. Sci. 28, 1-8, 1984.
  45. S.S.Hassan, P.K.Chaturvedi and S.N. Pandey : Effect of two graded doses of whole body X-irradiation and radioprotection by the use of S-phenetyl formamidino 4(N-ethyl isothioamide) morpholine dihydrochloride. Nucl. Med. 22, 237-245, 1983.
  46. S.S.Hassan and P.K.Chaturvedi : Response of whole body X-irradiation to inanition stress. Strahlentherapaie 159, 351-357, 1983.

 

BOOKS/ABSTRACT BOOKS:  

Editors/Associate Editor

  1. Molecular and clinical aspects of gonadal and nongonadal actions of gonadotropins. Eds CV Rao, USA, Anand Kumar, PK Chaturvedi Narosa publishing house, New Delhi (2010)
  2. Follicular Growth, Ovulation and Fertilization Eds: Anand Kumar, Amal K Mukhopadhya, Narosa publishing house, New Delhi. 2001.
  3. Advance Abstract of papers International symposium on Molecular & Clinical Aspects of the Regulation of Ovarian Function: Impact on the Reproductive Health of Women Eds: Anand Kumar, Amal K Mukhopadhya, 1999.
  4. Advance Abstract of papers Indo-Germen Satellite workshop Fertilization: Lessons from in-vitro Approaches Eds: Anand Kumar, Amal K Mukhopadhya, 1999.

 

 

Dr. Ashutosh Haldar

Dr. Ashutosh Halder

Professor & Head

Department of Reproductive Biology

 

 

Dr. Ashutosh Halder                                                        Specialization

Professor & Head                                                            Reproductive Genetics

यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.                                            Reproductive Endocrinology

MBBS (Cal), MD (OG, AIIMS), DNB (OG),                   Molecular Cytogenetics

DM (Med Genet, SGPGI), FAMS                                    Clinical Embryology

Commonwealth Scholar (Fetal Medicine)                           Teratology

(Ex Asst. Prof., Med Genet, SGPGIMS, Lucknow) 

 

Citations: near 1100+ (composite)

Google Scholar (1032)/Research Gate (845)/Expanded (>1100)

h-index            17

i10-index         29

  

Training

Obstetrics & Gynecology (AIIMS/MD+SR)

Medical Genetics (SGPGIMS/DM)

Fetal Medicine (Fetal Medicine Unit, Dept of Obst & Gyne, UCL, London)

Molecular Cytogenetics

(Galton Laboratory & Hamilton Laboratory, UCL, London;

Human Genetics, Virchow Klinicum, Berlin;

Cytogenetics, University of Clermont Ferrand, France;

Human Genetics, University of Bari, Uniba Biologia, Italy)

 

Teaching Courses Guided

MSc in Reproductive Biology & Clinical Embryology (AIIMS; since 2016)

PhD in Reproductive Biology (AIIMS; since 2001)

DM in Med Genet (SGPGI; between 1997-2001)

 

 

Training Provided

Long Term:                 Molecular Cytogenetics, Clinical Embryology, Reproductive Endocrinology, etc

National Workshop:     One-Week Workshop on Molecular Cytogenetics as Annual Event

 

Clinical/Laboratory Services Provided

Andrology (Primary Testicular failure), Malformation, Infertility, Reproductive Endocrine Disorders (PCOS, Hyperprolactinemia, POF, Primary Amenorrhoea, hypogonadotropic/ hypergonadotropic hypogonadism, etc)  M

Molecular Cytogenetics (FISH, microarray, etc)

Working on NIPT

Working on semen banking

 

Consultation/Research Areas

  1. Polycystic ovarian disease
  2. Premature ovarian failure
  3. Hyperprolactinemia
  4. Testicular maturation arrest
  5. Sertoli cell only syndrome
  6. Spermiation defect
  7. Microdeletion syndrome
  8. Recurrent Pregnancy Failure
  9. Recurrent Malformations
  10. Disorder of sex development
  11. Endometriosis
  12. Familial Reproductive Cancers
  13. Biological basis of skewed sex ratio
  14. NIPS
  15. Ovarian epithelial cancer

 

Research Conducted

Completed:

  1. Analysis for sperm aneuploidy of idiopathic oligoazoospermic & teratospermic men
  2. Evaluation of molecular basis of clinical aggressiveness in cervical carcinoma of young age
  3. Molecular basis of clinical aggressiveness in papillary thyroid carcinoma
  4. Role of Cytokines in Premature Ovarian Failure (collaborative)
  5. Double blind randomized clinical trial of polyherbal preparation Ashokarista on post- menopausal women (collaborative)
  6. Evaluation of anembryonic pregnancy and early missed abortion product for chromosomal aneuploidy and uniparental disomy by molecular method
  7. Chromosome aneuploidy and mosaicism in preimplantation embryo (human)
  8.  Chromosome aneuploidy and mosaicism in preimplantation embryo (mouse)
  9. Prevalence of 22q11 deletion syndrome in children with structural cardiac malformation: a tertiary care referral hospital-based study in Delhi
  10. Molecular Basis of Multiple Myeloma (collaborative)
  11. Rapid Aneuploidy Diagnosis by PRINS
  12. Spermiation Defect
  13. Genetic & Endocrine Evaluation of Primary Testicular Failure
  14. Understanding Dynamics of Skewed Sex Ratio
  15. Macroprolactinemia
  16. Premature ovarian failure
  17. Polycystic ovarian disease
  18. Testicular maturation arrest
  19. An investigation for sub-microscopic chromosomal imbalances and uniparental disomy by array comparative genomic hybridization (aCGH) in FISH negative clinically suspected 22q11.2 microdeletion syndromes
  20. Mechanism for phenotypic heterogeneity/variability in 22q11.2 microdeletion syndrome(ICMR)

 

Ongoing:

  1. An investigation to find out genetic factors in idiopathic familial ovarian failure
  2. Poly Cystic Ovarian Syndrome (PCOS): An investigation to find out reasons for discrepancy between hyperandrogenism (clinical) & hyperandrogenemia (biochemical) and underlying etiologic (epigenetic & genetic) factors
  3. Integrative Analysis of Ovarian Cancer Transcriptome to Identify Biomarkers and Potential Molecular Targets for Genome-guided Targeted Therapy
  4. An Investigation to find out mechanism for Phenotypic Heterogeneity/Variability in Microdeletion Syndrome

 

Submitted:

  1. Molecular basis of skewed sex ratio in high fat diet mice
  2. An investigation on underlying mechanism of PCOS in association with Bisphenol A and Advanced Glycation End products (EDCs)
  3. Non-Invasive Prenatal Screening (NIPS) of Common Chromosomal Abnormalities (aneuploidies and microdeletions) by Next Generation Sequencing

 

Visions

To create reproductive science center for the followings:

To develop reproductive genetics specialty

To develop NIPS facility

To develop reproductive endocrinology specialty

To develop semen cryopreservation (semen banking & AID) facility 

To develop gamete, embryo & gonad cryopreservation facility

To develop clinical embryology branches

To start courses (teaching/training) on Molecular Cytogenetics, Reproductive Genetics, Reproductive Endocrinology, Clinical Embryology & Cryopreservation, etc

 

 

Publications

Published Full Article
  1. Haldar A, Sharma AK, Phadke SR, Jain A, Agarwal SS. OEIS Complex with Cranio-Facial anomalies: Defect of Blastogenesis?  Am. J. Med. Genetics. 1994; 53: 21-23. (Journal Impact Factor: 2.048; Cited by 36)
  2. Sharma AK, Haldar A, et al. Postmortem Radiography of perinatal deaths: an aid to Genetic Counseling. Indian Pediatrics. 1994; 31(6): 702-706. (Journal Impact Factor: 1.036; Cited by 02)   
  3. Phadke SR, Haldhar A, et al.  GAPO Syndrome in a child without Dermal Hyaline Deposit. Am.  J. Med. Genetics. 1994; 51: 191-193. (Journal Impact Factor: 2.048; Cited by 09)
  4. Sharma AK, Haldar A, et al. Preaxial Brachydactyly with Abduction of Thumbs & Hallux Varus: a distinct entity. Am. J. Med. Genetics. 1994; 49(3): 274-277. (Journal Impact Factor: 2.048; Cited 07)
  5. Sharma AK, Phadke SR, Haldar A, et al. Jercolevine Syndrome: a case report. Indian Pediatrics. 1994; 31(6): 707-708. (Journal Impact Factor: 1.036; Cited by 06)    
  6. Sharma AK, Haldar A, et al. Marshall-Smith Syndrome: further observations. Indian Pediatrics. 1994; 31(8): 1098-1100. (Journal Impact Factor: 1.036; Cited by 07)
  7. Buckshee K, Haldar A, et al. Bioeffects of Diagnostic Ultrasound in Newborn. J. Obst. & Gynecol India. 1994; 44(1): 859-862. (Journal Impact Factor: NA; Cited by NA)
  8. Tutschek B, Sherlock J, Halder A, Delhanty J, Rodeck C, Adinolfi M. Isolation of Fetal Cells from transcervical samples by Micromanipulation: Molecular confirmation of their fetal origin and diagnosis of fetal aneuploidies. Prenatal Diagnosis. 1995; 15(10): 951-960. (Journal Impact Factor: 2.514; Cited by 62)*   
  9. Adinolfi M, Sherlock J, Tutschek B, Halder A, Delhanty J, Rodeck C. Detection of Fetal Cells in Transcervical Sample & Prenatal Diagnosis of Chromosomal abnormalities. Prenatal Diagnosis. 1995; 15(10): 943-950. (Journal Impact Factor: 2.514; Cited by 63)*
  10. Agarwal S, Kishore R, Haldar A, et al.  Outcome of pregnancy in women with Recurrent Spontaneous Abortion following Immunotherapy with Allogenic Lymphocytes. Human Reproduction.  1995; 10(9): 2280-2284. (Journal Impact Factor: 4.585; Cited by 15)
  11. Kishore R, Agarwal S, Haldar A, et al.  HLA sharing, Antipaternal Cytotoxic Antibodies & MLR Blocking Factors in women with Recurrent Abortions. J. Obstet. Gynaecol. Res. 1996; 22(2): 177-183. (Journal Impact Factor: 0.931; Cited by 35)   
  12. Sherlock J, Halder A, Tutschek B, Rodeck C, Adinolfi M. Prenatal detection of fetal aneuploidies using transcervical cell samples. J Med Genet. 1997; 34: 302-305. (Journal Impact Factor: 5.636; Cited by 42)
  13. Halder A & Tutschek B.  Analysis of meiotic segregation in human nondecondensed interphase spermatozoa by multicolor rapid direct FISH. Ind J Med Res. 1998; 107: 94-97. (Journal Impact Factor: 1.661; Cited by 06)
  14. Ruangvutilert P, Halder A, Jauniaux E, Arienzo M, Cirigliano V and Sherlock J.  A minimally invasive prenatal diagnosis technique for the collection of transcervical cells. Prenatal Neonatal Medicine 1998; 3: 294 - 296. (Journal Impact Factor: 0.544; Cited by 04)
  15. Halder A, Pahi J, Pradhan M, Pandey A, Gujral R, Agarwal SS. Iniencephaly: a report of 19 cases.  Ind Pediatrics. 1998; 35: 891 - 896. (Journal Impact Factor: 1.036; Cited by 11)
  16. Halder A, Pahi J, Sharma AK, Bhatia VL, Phadke RV, Gujral R & Agarwal SS. Osteodysplastic Primordial Dwarfism Type II with normal Mentation and delayed CNS Myelination. Am. J. Med. Genet. 1998; 80: 12-15. (Journal Impact Factor: 2.048; Cited by 14)*
  17. Pahi J, Phadke SR, Halder A, Agarwal SS, et al.  Does autopsy of antenataly diagnosed malformed fetuses aid genetic counseling? The National Medical Journal of India. 1998; 11(4): 169-170. (Journal Impact Factor: 0.908; Cited by 13)
  18. Jauniaux E, Halder A, Partington C. A case of partial mole associated with trisomy 13. Ultrasound Obstet Gynaecol. 1998; 11(1): 62-64. (Journal Impact Factor: 3.14; Cited by 23)
  19. Halder A & Park YK. Identification of the appropriate tissue from formalin fixed perinatal autopsy material for chromosomal ploidy detection by interphase FISH. Ind J Med Res. 1999; 110: 102-106. (Journal Impact Factor: 1.661; Cited by 08)
  20. Phadke SR & Halder A. Fluorescent in situ hybridization: A novel method to study chromosomes and genes. Perinatology 2000; 2(4): 203-210. (Journal Impact Factor: NA; Cited by NA)
  21. Halder A, Pahi J, Chadda V and Agarwal SS.  Sirenomelia Sequence associated with craniorachischisis totalis, limb reduction and primitive heart: a case report. Indian Pediatr. 2001; 38 (9): 1041-5. (Journal Impact Factor: 1.036; Cited by 13)
  22. Halder A. Trisomy 21 beyond 1st trimester: are they all mosaic? Evidence to support. Asian J Obs & Gynae Practice, 2002; 6 (2): 30-34. (Journal Impact Factor: NA; Cited by NA)
  23. Halder A, Agarwal S & Chaddha V. Genetic counseling in obstetric practice. Obstetrics & Gynecology Today 2002; VII (6): 310-318 (Journal Impact Factor: NA; Cited by NA).
  24. Chaddha V, Agarwal S, Phadke SR & Halder A (corresponding author). Low Level of Mosaicism in Atypical Prader Willi Syndrome: Detection using Fluorescent In Situ Hybridization. Indian Pediatrics 2003; 40: 166-168. (Journal Impact Factor: 1.036; Cited by 08)
  25. Agarwal S, Chadda V, Ram Sharan and Halder A (corresponding author). Rapid prenatal diagnosis of trisomy 18 by interphase FISH. Asian Journal of Obs & Gynae Practice 2003; 7 (1): 14–15 & 23. (Journal Impact Factor: NA; Cited by 02)
  26. Pandey MK, Halder A, Agarwal S, Srivastava M, Agarwal SS, Agrawal S. Immunotherapy in Recurrent Spontaneous Abortion: Randomised and Nonrandomised trials. The Internet Journal of Gynaecology and Obstetrics 2003; 2(1): rsa/xml (13 pages). (Journal Impact Factor: 0.16; Cited 04)
  27. Halder A, Panigrahi I & Pal L. Fowler like syndrome with extreme oligohydramnios & growth restriction and without muscle hypoplasia: first case from Indian subcontinent. Ind Pediat 2003; 40: 418-423. (Journal Impact Factor: 1.036; Cited by 08)
  28. Halder A, Chaddha V, Agarwal S, Fauzdar A. Absence of sperm meiotic segregation error of chromosomes 1, 9, 12, 13, 16, 18, 21, X and Y in a case of 100 % necrozoospermia. Asian J Androl. 2003 Jun; 5(2): 163-166. (Journal Impact Factor: 2.53; Cited by 11)
  29. Nagpure NS, Kushwaha B, Srivastava SK, Halder A and Ponniah AG. Comparative chromosome painting in fish using human sex chromosome probes. Indian J Fishery 2003; 50: 103-106. (Journal Impact Factor: 0.198; Cited by 03)
  30. Halder A, Halder S, Fauzdar A, Kumar A. Molecular approaches of chromosome analysis: an overview. Proc. Indian Nat. Sci. Acad. 2004; B70 (2): 153-221. (Journal Impact Factor: NA; Cited by 03)
  31. Halder A, Agarwal S, Pandey A. Iniencephaly and Chromosome Mosaicism: A Report of Two Cases. Congenital Anomalies 2005; 45: 102-105. (Journal Impact Factor: 0.783; Cited by 09)
  32. Halder A, Fauzdar A, Kumar A. Serum Inhibin B and Follicle Stimulating Hormone Levels as Markers in the Evaluation of Azoospermic Men: A Comparison. Andrologia 2005; 37: 173-179. (Journal Impact Factor: 1.172; Cited by 30)
  33. Halder A, Fauzdar A, Kabra M and Saxena A. Detection of 22q11.2 hemizygous deletion by interphase FISH in a patient with features of CATCH22 Syndrome. Ind Pediatr. 2005; 42: 1236-1239. (Journal Impact Factor: 1.036; Cited by 03)
  34. Halder A, Halder S, Fauzdar A. A Preliminary Investigation on Molecular Basis for Clinical Aggressiveness in Cervical Carcinoma by Comparative Genomic Hybridization and Conventional Fluorescent In-situ Hybridization. Ind J of Med Res. 2005; 122: 434-446. (Journal Impact Factor: 1.661; Cited by 08)*
  35. Halder A. Placental chimerism in early human pregnancy. Ind J of Hum Genet 2005; 11 (2): 84-88. (Journal Impact Factor: NA; Cited by 05)
  36. Halder A and Fauzdar A. Extreme Skewing of Sex Ratio and Low Aneuploidy in Recurrent Early Missed Abortion. Ind J Med Res 2006; 124: 41-50. (Journal Impact Factor: 1.661; Cited by 14)*
  37. Halder A. Skewed Sex Ratio in India. Ind J Med Res 2006; 124: 583-584. (Journal Impact Factor: 1.661; Cited by 06)*
  38. Halder A, Fauzdar A. Potential use of blood, buccal and urine cells for rapid noninvasive diagnosis of suspected aneuploidy using FISH. Journal of Clinical & Diagnostic Research 2007; 1 (2): 32-38. (Journal Impact Factor: 0.14; Cited by 07)
  39. Halder A, Fauzdar A, Ghosh M, Kumar A. Serum Inhibin B: A Direct, Precise & Noninvasive Marker of Ovarian Function. Journal of Clinical & Diagnostic Research. 2007; 1(3): 131-137. (Journal Impact Factor: 0.14; Cited by 04)
  40. Halder A. Nonimmunologic Hydrops Fetalis Associated with True Knot of Umbilical Cord: A Necropsy Study. J Turkish German Gynecol Assoc. 2007; 8(4): 420-423. (Journal Impact Factor: 0.13; Cited by 05)
  41. Halder A. Unexplained Ten Consequetive Early Third Trimester Intrauterine Fetal Deaths: A Diagnostic Dilema. The Internet Journal of Gynecology and Obstetrics. 2007; Volume 7, Number 2. (IUD_0910.doc) (Journal Impact Factor: 0.16; Cited by 02)
  42. Halder A. Premature Graying of Hairs, Premature Aging and Predisposition to Cancer in Jajjal, Punjab: A preliminary observation. Journal of Clinical & Diagnostic Research 2007; 6: 577-580. (Journal Impact Factor: 0.14; Cited by 06)*
  43. Halder A, Gupta RK. Male like external genitalia with epididymis in a case of 46,XX disorder of sex development due to  congenital adrenal hyperplasia. Journal of Research in Medical Sciences 2008; 13(3): 141-145. (Journal Impact Factor: 0.608; Cited by 02)
  44. Halder A, Jain M, Kabra M, Gupta N. Mosaic 22q11.2 microdeletion syndrome: diagnosis and clinical manifestations of two cases.  Molecular Cytogenetics 2008; 1: 18. (Journal Impact Factor: 2.66; Cited by 24)*
  45. Fauzdar A, Sharma RK, Kumar A, Halder A. A Preliminary Study on Chromosome Aneuploidy and Mosaicism in Early Preimplantation Human Embryo by Fluorescence In Situ Hybridization. Ind J Med Res 2008; 128 (3): 287-293 (Journal Impact Factor: 1.661; Cited by 02)
  46. Fauzdar A, Halder A, Kumar A. Effect of gonadotropins on chromosome aneuploidy, chromosome mosaicism and skewed sex ratio in mouse preimplantation embryos. Ind J Med Res 2009; 129: 669-675 (Journal Impact Factor: 1.661; Cited by 04)
  47. Yadav N, Sumod K, Kumar S, Jain M, Halder A, Saxena R, Mukhopadhyay A. Therapeutic effect of bone marrow-derived liver cells in phenotypic correction of murine hemophilia A. Blood; 2009 114: 4552-4561 (Journal Impact Factor: 9.775; Cited by 19)
  48. Shukla B, Agarwal S, Suri V, Pathak P, Sharma MC, Gupta D, Sharma BS, Suri A, Halder A, Sarkar C. Assessment of 1p/19q status by fluorescence in situ hybridization assay: A comparative study in oligodendroglial, mixed oligoastrocytic and astrocytic tumors. Neurol India 2009; 57: 559-566. (Journal Impact Factor: 1.084; Cited by 08)
  49. Halder A.  Amniotic Band Syndrome and/or Limb Body Wall Complex: Split or Lump. The Application of Clinical Genetics 2010; 3: 7-15. (Journal Impact Factor: 0.7; Cited by 10)
  50. Halder A.  46, XY Disorder of Sex Development with Mullerian Ducts Remnants. Journal of Clinical & Diagnostic Research 2010; 4: 2169-2174 (Journal Impact Factor: 0.14; Cited by 01)
  51. Halder A, Jain M, Chaudhary I, Kabra M. Prevalence of 22q11.2 microdeletion in 146 patients with cardiac malformation in a referral hospital of North India.  BMC Medical Genetics 2010; 11: 101. (Journal Impact Factor: 2.45; Cited by 14)
  52. Halder A, Jain M, Chaudhary I and Varma B. Chromosome 22q11.2 microdeletion in monozygotic twins with discordant phenotype and deletion size. Molecular Cytogenetics 2012; 5:13 (JIF 2.41; ICV 5.61) (Journal Impact Factor: 2.66; Cited by 17)*
  53. Jain M, Halder A. Sertoli cell only syndrome: Status of sertoli cell maturation and function. Indian J Endocr Metab 2012; 16: S514-515. (Journal Impact Factor: NA; Cited by 05)
  54. Halder A, Jain M and Chaudhary I. Rapid Detection of Chromosome X, Y, 13, 18 & 21 Aneuploidies by Primed In Situ Labeling/Synthesis (PRINS) Technique. Ind J Hum Genet 2013; 19 (1): 14-17. (Journal Impact Factor: NA; Cited by 02)
  55. Jain M, Mohan V, Chaudhary I, Halder A. Sertoli cell only syndrome and glaucoma in a SRY positive XX infertile male. Journal of Clinical & Diagnostic Research 2013; 7 (7): 1457-1459. (Journal Impact Factor: 0.14; Cited by 03)
  56. Halder A, Jain M, Chaudhary I, Gupta N and Kabra M. Fluorescence in-situ hybridization (FISH) using non-commercial probes in the diagnosis of clinically suspected microdeletion syndromes: an experience with 301 cases. Ind J Med Res 2013; 138: 135-142. (Journal Impact Factor: 1.661; Cited by 04)
  57. Halder A. Advances in Cytogenetics (editorial). JBR Journal of Clinical Diagnosis and Research. 2013; 16:e101.doi:10.4172/jcdr.1000e101  Volume1 Issue1 1000e101. http://dx.doi.org/ 10.4172/ jcdr.1000e101 (Journal Impact Factor: NA; Cited by NA)
  58. Halder A. Disorder of Sex Development: spectrum of disorder in a referral tertiary care hospital in Northern India. The Global Journal of Human Genetics & Gene Therapy. 2013; 1 (2): 77-89 (Journal Impact Factor: NA; Cited by NA)
  59. Halder A. Cytogenetics to Cytogenomics: transition from Chromosome to DNA sequence. The Global Journal of Human Genetics & Gene Therapy. 2013; 1 (2): 90-104 (Journal Impact Factor: NA; Cited by NA)
  60. Halder A, Jain M, Chawdhary I, Kumar G, Das TK, Gupta YK. Dark Colored Semen in Non-obstructive Azoospermia: A Report of 4 Cases, Andrologia 2014; 46 (3): 316–321. (Journal Impact Factor: 1.172; Cited by NA)
  61. Halder A. Lethal Developmental Defects: An Overview. Open Journal of Obstetrics and Gynecology 2014; 4: 1006-1036 (Journal Impact Factor: 0.24; Cited by NA)
  62. Chaudhary I, Jain M, Halder A. Sperm sex ratio (X:Y ratio) and its variations. Austin J Reprod Med Infertil. 2014;1(1): 7 (arjm-v1-id1003) (Journal Impact Factor: NA; Cited by NA)
  63. Halder A. Genetic counseling for infertile couples. ISSRF News Letter 2015; sp issue 16: pp 14-19 (Journal Impact Factor: NA; Cited by NA)
  64. Halder A. Canceromics and P3 medicine (editorial). JBR J Clin Diagn Res 2015; 3: 1 (1000e104). doi:10.4172/jcdr.1000e104 (2 pages)
  65. Sharma P, Gupta N, Roychowdhury M, Phadke SR, Sapra S, Halder A, Ghosh M and Kabra M. Williams-Beuren syndrome: Delineation of clinical phenotype and diagnostic utility of MLPA: Experience of 43 patients from a tertiary care centre in India. Cytogenetic and Genome Research 2015: Sep 10 (DOI:10.1159/000439205)
  66. Halder A, Jain M and Kumar P. Primary Testicular Failure: An Overview. J Clin Diagn Res 2015; 3: 1 (1000e105). doi:10.4172/jcdr.1000e105 (5 pages)
  67. Halder A. Reproductive Genetic Counseling in Genomic Era. EC Gynaecology2015; 2 (1): 132-148.
  68. Halder A. Approach to Fetal Malformations. In: Proceeding (The wonderful world of clinical genetics) of IAMGCON 2015 Jodhpur, India; pp.56-69.
  69. Halder A, Jain M, Kalsi AP. SNP Microarray in FISH Negative Clinically Suspected 22q11.2 Microdeletion Syndrome. Scientifica 2016; 18 pages (http://dx.doi.org/10.1155/2016/5826431)
  70. Halder A. Reproductive Genetics (editorial). JBR Journal of Clinical Diagnosis and Research 2016; 4: 106 (2 pages). doi:10.4172/2376-0311.1000e106
  71. Halder A. Approach to Prenatal Fetal Malformations. EC Gynaecology2016; 3 (3): 294-307.
  72. Halder A. Non-invasive Prenatal Testing. EC Gynaecology2016; 3 (5): 365-367.
  73. Jain M, Kalsi AK, Srivastava A, Gupta YK, Halder A. High serum estradiol and heavy metals responsible for human spermiation defect. J Clin Diag and Res 2016; Dec;10(12):RC09-RC13. doi: 10.7860/JCDR/2016/22483.8990.
  74. 74.  Halder A, Kumar P, Jain M. Primary testicular failure: A search for ideal biomarkers. Ind J Endo and Meta 2017; 21 (suppl 1): pp S2.
  75. Halder A, Kumar P, Jain M, Iyer VK. Copy number variations in testicular maturation arrest. Andrology 2017; 5 (3): 460-472. doi: 10.1111/andr.12330.
  76. Halder A, Kumar P, Jain M, Kalsi AP. Genomics: Tool to predict & prevent male infertility. Front Biosci (Schol Ed). 2017; 9: 448-508.
  77. Kumar P, Jain M, Kalsi AK, Halder A. Molecular characterization of a case of dicentric Y presented as non-obstructive azoospermia with testicular early maturation arrest. Andrologia, 2017; 50: e12886. DOI: 10.1111/and.12886
  78. Kalsi AK, Halder A, Jain M, Chaturvedi PK, Sharma JB. Prevalence and Reproductive Manifestations of Macroprolactinemia. Endocrine 2019; 63: 332-340
  79. Halder A, Jain M, Kalsi APK. Mosaicism in 22q11.2 Microdeletion Syndrome. J Clin Diagn Res. 2018; 12 (11): GC01-GC06
  80. Kalsi AK, Halder A, Jain M, Chaturvedi PK, Mathew M, Sharma JB. Association of raised levels of IL-4 and anti-TPO with hyperprolactinemia. Am J Reproductive Immunology 2019; 81:  e13085 (doi: 10.1111/aji.13085)
  81. Kalsi AK, Halder A, Jain M, Srivastava A. Association of Cadmium, Chromium, Manganese and Lead with hyperprolactinemia. Journal of Clinical and Diagnostic Research 2020; 14: 4-7.
  82. Rishi I, Halder A, Sharma JB, Jain M, Sharma M. Single Strand Conformation Polymorphism and Sequencing of HS6ST2 Gene in Patients of Idiopathic Premature Ovarian Failure. Journal of Clinical and Diagnostic Research. 2020; 14(2): GC01-GC08
  83. Jain P, Wadhwa N, Joshi MK, Jain M, Halder A, Mishra K. Cellular mesenchymal epithelial transition (C-MET) gene copy number variation in gastric adenocarcinoma: A pilot search for new marker for targeted therapy in HER-2/neu resistance. Indian J Pathol Microbiol. 2020 Jan-Mar; 63(1): 86-89. doi: 10.4103/IJPM.IJPM_396_19. PubMed PMID: 32031129.
  84. Jain M, Sharma A, Halder A, Kaushal S. Intra-individual genomic variation study in tissues (Blood vs. Testis) through SNPs Microarray: Case report in two idiopathic Sertoli cell only Syndrome patients (SCOS). Journal of Reproduction & Infertility 2020 (accepted)
  85. Halder A and Pandey D. CFTR gene variants in Indian CBAVD and its relevance in genetic counselling. IJMR 2020 (accepted; commentary).
  86. Halder A, Rana R, et al. Salient yet silent: A need for strategies to cope with violence against infertile women during COVID-19 pandemic. Indian Journal of Public Health 2020 (submitted)
  87. Manisha Singh, Manish Jain, Samrat Bose, Ashutosh Halder, Tapas Chandra Nag, Amit Kumar Dinda, Sujata Mahanti. 22(R)-hydroxycholesterol for differentiation of MSCs & amelioration of Parkinsonian symptoms in rats. The EMBO Journal. 2020 (submitted)
  88. Wadhwa N, et al. Human telomerase RNA component (hTERC) gene expression and chromosome 7 ploidy correlates positively with histologic grade of cervical intra-epithelial neoplasia. Cytopathology. 2020 (CYT-2020-0122;submitted)
  89. Sharma M, Bidhan J, Halder A, Sharma JB, Mahey R, Gupta S. A Preliminary Study of Human Sperm Citrate Synthase Expression in Patients with Failed ICSI Cycles. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 2020 (IJRCOG-8749; submitted)
  90. Jain M, Halder A, et al. Identification of Genomic imbalances (CNVs as well as LOH) in Sertoli Cell Only Syndrome cases through Cytoscan Microarray. Andrology 2020 (submitted).
  91. Halder A, Kumar H, Kalsi AK, Jain M. Dihydrotestosterone: a potential biomarker of hyperandrogenaemia in PCOS. 2020 Reprod Med and Biol (submitted)
  92. Kalsi AK, Halder A, Jain M. An investigation on bone mineral density in hyperprolactinemia. 2020 (submitted)
  93. Halder A, Chaudhary I, Jain M. Sex Ratio Trajectory in Mouse. Syst Biol Rep Med 2020 (submitted)

 

Published Abstract (Indexed Only)
  1. Delhanty JDA, Sherlock J, Tutschek B, Halder A, Rodeck CH, Adinolfi M. Detection & analysis of fetal cells in TCC using FISH & PCR amplification of unique fetal DNA sequences. Am. J. Hum. Genet. 1995; 57(4): A32 (159).
  2. Tutschek B, Sherlock J, Halder A, et al. Collection of fetal cells from cervical canal during 1st trimester of pregnancy: Sampling technique, molecular analysis and isolation of purely fetal material. Europe. J Hum. Genet. 1996; 4(suppl.1): 20 (1.014).
  3. Sherlock J, Tutschek B, Halder A, et al. Prenatal diagnosis of 4 Chromosome anomalies from TCC. Europ.J. Hum. Genet. 1996; 4 suppl.10: 126 (9.026).
  4. Halder A, Tutschek B. Analysis of meiotic segregation in human nondecondensed interphase spermatozoa by multi color directs FISH. J Med Genet. 1996; 33 (suppl.1); S48 (12.001).
  5. Ruangvutilert P, Halder A, Sherlock J, Jauniaux E, Anenzo MP, Adinolfi M. A minimally invasive prenatal diagnosis technique for the collection of transcervical cells. Am J Hum Genet 1997; 61(4) supplement: Abst. No. 924, Page A 161.
  6. Halder A & Park YK. Rapid detection of ploidy in paraffin embedded formalin fixed tissue in perinatal autopsy material by interphase FISH: a search for the right tissue. Am J Hum Genet 1998; 63(4) supplement: abstract No. 871.
  7. Halder A, Park YK, et al. Sex Chromosome chimerism in early pregnancy: a report of 3 cases. Eu J Hum Genet 1999; 7: P251 (May, Suppl.)
  8. Halder A, Park YK, et al. Trisomy 21 beyond first trimester: are they all mosaic? Evidence to support. Cytogent Cell Genet 1999; 85: P633 (July, Suppl.).
  9. Halder A, Fauzdar A and Kumar A. Rapid Molecular Approaches for Aneuploidy Diagnosis. Int J Hum Genet. 2004; Sup. 1: 31-38.
  10. Halder A, Fauzdar A & Kumar A. Extreme Skewing of Sex Ratio in Recurrent Early Missed Abortions. In Abstract Book of the 12th World Congress on Human Reproduction (Venezia, March 10-13, 2005); Electronic Publication (www.humanrep2005.org).
  11. Halder A, Halder S, Fauzdar A. A Preliminary Investigation on Molecular Basis for Clinical Aggressiveness in Cervical Carcinoma by Comparative Genomic Hybridization and Conventional Fluorescent In-situ Hybridization. J of Cancer Research & Therapeutics 2006; 2: S15.
  12. Halder A. Dynamics of Pre zygotic and post zygotic Sex Ratio. Journal of Andrology 2009; pp. 70. Allen Press, Inc PO Box 368, lawrence, KS 66044 USA: (34th American Society of Andrology Annual Meeting, Philadelphia, PA, USA, 2009)
  13. Verma R, Kumar L, Halder A, Sharma A, Gupta R, Saxena R. Multiple Myeloma: Clinical Implications of Cytogenetic Aberrations on Selected Plasma Cells on Conventional Cytogenetics and Interphase Flourescence In Situ Hibridization (FISH). Blood 2010; 116 (21): 4987
  14. Verma R, Kumar L, Gupta R, Halder A, Sharma A, Saxena R. Impact of cytogenetics on clinical outcome in multiple myeloma: A risk stratification model. ASCO Annual Meeting Proceedings 2011; 29 (15_suppl): e18576
  15. Jain M, Halder A. Sertoli cell only syndrome: Status of sertoli cell maturation and function. Indian J Endocr Metab 2012; 16: S514-515.
  16. Halder A, Jain M, Chaudhary I, Mohan V, Kumar P. Suspected microdeletion syndromes and molecular cytogenetic techniques: an experience with 330 cases. In 63rd annual conference of ASHG 2013, Boston, USA (3246T), p583
  17. Halder A, Jain M, Chaudhary I, Mohan V, Kumar P. Suspected microdeletion syndromes and molecular cytogenetic techniques: an experience with 330 cases. Molecular Cytogenetics 2014; 7 (Suppl 1): 20 (O7). DOI: 10.1186/1755-8166-7-S1-O7. ISSN: 1755-8166.
  18. Halder A, Jain M, Kumar P. Primary Testicular Failure: Genotype Phenotype Correlation of 140 cases. Andrology 2014; 2 (suppl. 1): 66-67 (poster no.16).
  19. Halder A.  Assessment of DNA microarray for evaluation of microdeletion syndromes. Ind J Hum Genet 2014; 20 (suppl 1): S23
  20. Jain M, Halder A. A Preliminary Study on Human Spermiation Defect. Ind J Hum Genet 2014; 20 (suppl 1): S116.
  21. Halder A, Kumar P and Jain M. Genomic and epigenomic factors in male infertility. In: Cross breed male infertility and bovine genomics. Edited by De S, NDRI, Karnal, India. 2016;pp.80.(http://cbp.icar.gov.in/Data/Coordinator/7100/Mannual%20S%20De%20Cross % 20 breed%20male%20infertility.pdf)
  22. Jasrotia S, Gupta R, Iqbal S, Sharma A, Halder A, Kumar L. Dysregulation of nuclear factor-kappaB pathway in multiple myeloma patients at diagnosis and relapse. J Clin Oncol 34, 2016 (suppl; abstr 8050)
  23. Halder A, Kumar P and Jain M. Primary testicular failure: a search for ideal biomarkers. Ind J End & Meta 2017; 21 (suppl 1): pp. S2. March issue (IJEM_420_16)
  24. Halder A, Kumer H, Kalsi AK, Jain M. Polycystic ovary syndrome: The pros and cons of various diagnostic criteria and investigation to find out associations of various factors implicated with PCOS. Ind J Endoc Metab 2017 suppl (poster no. 123; IJEM_466_17)
  25. Kalsi AK, Jain M, ….., Halder A. Macroprolactinemia: prevalence and etiopathologic associations. Ind J End Metab 2017 suppl (poster no. 144; IJEM_482_17)
  26. Halder A, Kumar H, Kalsi AK, Jain M. Dihydrotestosterone (DHT): a potential biomarker of hyperandrogenaemia in polycystic ovary syndrome. Ind J End Metab 2018 suppl. IJEM_429_18R2.
  27. Kalsi AK, Halder A, Jain M. An investigation on bone mineral density in hyperprolactinemia. Indian Journal of Endocrinology and Metabolism 2019; 23 (suppl 1): pp. S36 (IJEM_314_19)

 

Books/Book Chapters/Monographs/Proceedings
  1. Halder A. Advances in Human Cytogenetics: an overview. In: Advances in Human Cytogenetics (CME Monograph Series II of National Academy of Medical Sciences of India). Editor: Halder A. 2002; pp.1-38.
  2. Halder A, Fauzdar A & Kumar A. Extreme Skewing of Sex Ratio in Recurrent Early Missed Abortions. In: Human Reproduction; Editors: Genazzani AR, Schenker J, Artini PG, Simoncini T; Publisher: CIC Edizioni Internazionali, Roma, 2005; vol. 2 pp. 69-73.
  3. Halder A, Fauzdar A & Kumar A. Do gonadotropins used for ovarian stimulation in assisted reproduction cause increase in chromosome aneuploidy, chromosome mosaicism and skewed sex ratio in embryos? In: Gonadal and Nongonadal Actions of Gonadotropins. Editor: Kumar A, Rao CV, Chaturvedi PK; Publisher: Narosa, New Delhi, 2010; vol. 1 pp.327-337.
  4. Halder A. Clinical & Molecular Cytogenetics. In: API text book of medicine Editor: YP Munjal), 9th edition. 2012, Vol.1, Ch 3. pp 180-188.
  5. Halder A & Manish Jain. Molecular Cytogenetics Manual. 2012
  6. Handbook on Medical Genetics and Genetic Counseling. Edited by RK Marwaha, I Panigrahi & A Halder. Noble Vision (Medical Book Publishers; ISBN No. 978-81-906227-4-5) First Edn. 2013.
  7. Halder A. Molecular cytogenetics. Chapter 26. In: Handbook on Medical Genetics and Genetic Counseling. Edited by RK Marwaha, I Panigrahi & A Halder. Noble Vision (Medical Book Publishers; ISBN No. 978-81-906227-4-5) First Edn. pp.181-186; 2013.
  8. HosseiniA & Halder A. Genornics and human genome project. Chapter 27. In: Handbook on Medical Genetics and Genetic Counseling. Edited by RK Marwaha, I Panigrahi & A Halder. Noble Vision (Medical Book Publishers; ISBN No. 978-81-906227-4-5) First Edn. pp.187-189; 2013
  9. Halder A. Clinical, Conventional & Molecular Cytogenetics. In: API textbook of medicine Editor in chief: Dr.YP Munjal, 10th edition. 2014 (released on March 2015), Vol.1, Ch 3.
  10. Halder A. Approach to Fetal Malformations. In: Proceeding (The wonderful World of Clinical Genetics) of IAMGCON 2015 Jodhpur, India; pp.56-69.
  11. Halder A. Genetic counseling for infertile couples. ISSRF News Letter 2015; sp issue 16: pp 14-19.
  12. Halder A. Clinical, Conventional & Molecular Cytogenetics. In: API textbook of medicine Editor in chief: Dr. Sandhya A. Kamath, 11th edition. 2018, Vol.1, Ch 3
  13. Jain M, Halder A. Y Chromosome. In: Basics of Human Andrology: A Text Book. Editors: A Kumar, M Sharma (Springer, New Delhi. First Edn. 2017; Part I, chapter 7, pp77-98)
  14. Jain M, Kumar P, Halder A. Primary testicular failure. In: Basics of Human Andrology. Editors: A Kumar, M Sharma (Springer, New Delhi. First Edn. 2017; Part VII, chapter 24, pp417-436)

 

Miscelleneous

  1. Contribution in commercial syndrome data base computer software programme: London Dysmorphology Data Base, London, UK (LDDB) on Osteodysplastic Syndrome
  2. Contribution in commercial syndrome data base computer software program: Possum Database, Melbourne, Australia on Osteodysplastic Syndrome
  3. Contributed to London Dysmorphology & Neurogenetics Databases for its Ophthalmo-genetics or GENEEYE (latest addition) for its photographic library on Amniotic bands of early amnion rupture.        

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